Deciphering the mechanism of protein aggregation and effects of inhibitors using single-molecule mass photometry
Aaron Lyons, Simanta Sarani Paul, Jack E. MacArthur, Grace N. Hoffman, Allan Yarahmady, Sue‐Ann Mok, Michael T. Woodside
This study uses single-molecule mass photometry to directly observe protein aggregation kinetics and identify inhibitor effects on aggregation mechanisms.
Proceedings of the National Academy of Sciences · Jul 22, 2026Peer-reviewedBiophysics