Author

Simon Coetzee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Beth Y. KarlaniD· 1 shared Dennis J. HazelettiD· 1 shared Felipe Segato· 1 shared Houtan NoushmehriD· 1 shared Janet M. Lee· 1 shared Ji-Heui SeoiD· 1 shared Kate LawrensoniD· 1 shared Marcos A.S. Fonseca· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Beth Y. KarlanORCID

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1 paper

Recent·Most cited

Integrated Molecular Profiling Studies to Characterize the Cellular Origins of High-Grade Serous Ovarian Cancer

Kate Lawrenson, Marcos A.S. Fonseca, Felipe Segato, Janet M. Lee, Rosario I. Corona, Ji-Heui Seo, Simon Coetzee, Yvonne G. Lin, Tanja Pejovic, Paulette Mhawech-Fauceglia, Ronny Drapkin, Beth Y. Karlan, Dennis J. Hazelett, Matthew L. Freedman, Simon A. Gayther, Houtan Noushmehr

The paper uses transcriptomic and epigenomic profiling to show that high-grade serous ovarian cancers predominantly originate from fallopian tube secretory epithelial cells, with distinct transcription factors driving tumorigenesis based on cell-of-origin.

bioRxiv · May 25, 2018 · PreprintCancer Biology