Author

Felipe Segato

Universidade de São Paulo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Beth Y. KarlaniD· 2 shared Houtan NoushmehriD· 2 shared Janet M. Lee· 2 shared Kate LawrensoniD· 2 shared Matthew L. FreedmaniD· 2 shared Simon A. GaytheriD· 2 shared Alexander GuseviD· 1 shared Bogdan PaşaniuciD· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenomics

Beth Y. KarlanORCID

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2 papers

Recent·Most cited

Multi-Tissue Transcriptome-Wide Association Studies Identify 21 Novel Candidate Susceptibility Genes for High Grade Serous Epithelial Ovarian Cancer

Alexander Gusev, Kate Lawrenson, Felipe Segato, Marcos A. Fonseca, Siddhartha Kar, Kevin C. Vavra, Janet M. Lee, Tanya Pejovic, Beth Y. Karlan, Matthew L. Freedman, Houtan Noushmehr, Paul D.P. Pharoah, Bogdan Paşaniuc, Simon A. Gayther

This study identifies 21 novel candidate susceptibility genes for high grade serous ovarian cancer using transcriptome-wide association analysis across multiple tissue types.

bioRxiv · May 25, 2018 · PreprintGenomics

Integrated Molecular Profiling Studies to Characterize the Cellular Origins of High-Grade Serous Ovarian Cancer

Kate Lawrenson, Marcos A.S. Fonseca, Felipe Segato, Janet M. Lee, Rosario I. Corona, Ji-Heui Seo, Simon Coetzee, Yvonne G. Lin, Tanja Pejovic, Paulette Mhawech-Fauceglia, Ronny Drapkin, Beth Y. Karlan, Dennis J. Hazelett, Matthew L. Freedman, Simon A. Gayther, Houtan Noushmehr

The paper uses transcriptomic and epigenomic profiling to show that high-grade serous ovarian cancers predominantly originate from fallopian tube secretory epithelial cells, with distinct transcription factors driving tumorigenesis based on cell-of-origin.

bioRxiv · May 25, 2018 · PreprintCancer Biology