Site-specific recombination between inverted target sites generates dicentric/acentric chromosomes.
Simon William Abraham Titen, Makenna T. B. Johnson, Mario R. Capecchi, Kent G. Golic
The paper shows that recombination between inverted target sites on sister chromatids produces dicentric and acentric chromosomes, which can negatively affect cell viability and behavior.
Genetics · Jun 25, 2020Peer-reviewedGenetics