Author

Simone Gardini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfonso TrezzaiD· 1 shared Daniele IovinelliiD· 1 shared Monica BianchiniiD· 1 shared Neri NiccolaiiD· 1 shared Ottavia SpigaiD· 1 shared Pietro BonginiiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Alfonso TrezzaORCID

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1 paper

Recent·Most cited

Some Mendelian Disorders could be fixed with a pill? A Structural Bioinformatic investigation

Pietro Bongini, Daniele Iovinelli, Alfonso Trezza, Monica Bianchini, Ottavia Spiga, Simone Gardini, Neri Niccolai

The paper investigates Gly mutations in Mendelian disorders using ClinVar data, finding that bulky hydrophobic amino acid substitutions reduce protein stability and that Gly mutations may create binding pockets targetable for drug development.

bioRxiv · Oct 20, 2022 · PreprintBioinformatics