Author

Pietro Bongini

University of SienaORCID 0000-0001-9074-0587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfonso TrezzaiD· 1 shared Daniele IovinelliiD· 1 shared Monica BianchiniiD· 1 shared Neri NiccolaiiD· 1 shared Ottavia SpigaiD· 1 shared Simone Gardini· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Alfonso TrezzaORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 20, 2022

Some Mendelian Disorders could be fixed with a pill? A Structural Bioinformatic investigation

Pietro Bongini, Daniele Iovinelli, Alfonso Trezza…·Neri Niccolai

The paper investigates Gly mutations in Mendelian disorders using ClinVar data, finding that bulky hydrophobic amino acid substitutions reduce protein stability and that Gly mutations may create binding pockets targetable for drug development.

DOI 10.1101/2022.10.20.513070

humanprotein structure

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