Author

Monica Bianchini

University of SienaORCID 0000-0002-8206-8142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alfonso TrezzaiD· 1 shared Daniele IovinelliiD· 1 shared Federica BacciniiD· 1 shared Filippo GeraciiD· 1 shared Neri NiccolaiiD· 1 shared Ottavia SpigaiD· 1 shared Pietro BonginiiD· 1 shared Simone Gardini· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperBioinformatics

Alfonso TrezzaORCID

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2 papers

Recent·Most cited

Some Mendelian Disorders could be fixed with a pill? A Structural Bioinformatic investigation

Pietro Bongini, Daniele Iovinelli, Alfonso Trezza, Monica Bianchini, Ottavia Spiga, Simone Gardini, Neri Niccolai

The paper investigates Gly mutations in Mendelian disorders using ClinVar data, finding that bulky hydrophobic amino acid substitutions reduce protein stability and that Gly mutations may create binding pockets targetable for drug development.

bioRxiv · Oct 20, 2022 · PreprintBioinformatics

Graph-based integration of histone modifications profiles: haematopoietic cell differentiation as a case study

Federica Baccini, Monica Bianchini, Filippo Geraci

The paper integrates histone modification profiles using graph-cut techniques to study myeloid and lymphoid cell differentiation in haematopoiesis, finding that all modifications contribute equally to differentiation.

bioRxiv · Oct 22, 2020 · PreprintBioinformatics