Sub-chronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice
Natalie A. Trigg, John Even Schjenken, Jacinta Hope Martin, David Anthony Skerrett-Byrne, Shannon P. Smyth, Ilana R. Bernstein, Amanda L. Anderson, Simone J. Stanger, Ewan N. A. Simpson, Archana Tomar, Raffaele Teperino, Colin C. Conine, Geoffry Nunzio De Iuliis, Shaun D. Roman, Elizabeth G. Bromfield, , Brett Nixon
This study shows that sub-chronic heat stress alters sperm small non-coding RNA profiles in mice, leading to accelerated embryonic development and fetal weight gain.
Proceedings of the National Academy of Sciences · Nov 11, 2024Peer-reviewedCell Biology