Development of a thermostable and broadly neutralizing pan-sarbecovirus vaccine candidate
Simran Srivastava, Sahil Kumar, Suman Mishra, Raju Rajmani, Randhir Singh, Somnath Dutta, Rajesh P. Ringe, Raghavan Varadarajan
This paper develops a thermostable, broadly neutralizing pan-sarbecovirus vaccine candidate using stabilized RBD derivatives from multiple sarbecovirus clades, showing enhanced thermal stability and immunogenicity in mice.
ACS Infectious Diseases · Dec 23, 2025Peer-reviewedImmunology