Author

Sini Miettinen

University of Helsinki

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Éric DufouriD· 1 shared Grzegorz L. CiesielskiiD· 1 shared Howard Trevor JacobsiD· 1 shared Jose M. González de CózariD· 1 shared Laurie S. Kaguni· 1 shared Maria Carretero· 1 shared Markku T VarjosaloiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Éric DufourORCID

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1 paper

Recent·Most cited

A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1

Jose M. González de Cózar, Maria Carretero, Grzegorz L. Ciesielski, Sini Miettinen, Markku T Varjosalo, Laurie S. Kaguni, Éric Dufour, Howard Trevor Jacobs

The paper investigates the role of a second hybrid-binding domain in Drosophila RNase H1, showing it enhances catalytic activity and processivity by facilitating dissociation of the active site from the product.

The Journal of Biochemistry · Jun 18, 2020Peer-reviewedMolecular Biology