Howard Trevor Jacobs

The paper shows that nuclear genetic background significantly affects the phenotype of the Drosophila tko25t mitochondrial mutant, with varying severity across different nuclear backgrounds.

The paper examines how changes in RNA polymerase concentration affect gene expression in E. coli, finding that mid-term responses correlate with transcription factor network topology.

The paper investigates the role of a second hybrid-binding domain in Drosophila RNase H1, showing it enhances catalytic activity and processivity by facilitating dissociation of the active site from the product.

This study shows that overexpressing spargel in a Drosophila mitochondrial disease model has minimal effects on phenotype and gene expression.