Single Cell Transcriptomics and Surface Protein Expression Reveal Distinct Cellular and Molecular Phenotypes in Human RPESC-RPE and PSC-RPE
Swapna Nandakumar, Farhad Farjood, Taylor B. Bertucci, Steven Lotz, Skanda Sai, Yue Wang, Jade A. Kozak, Brigitte L. Arduini, Jeffrey H. Stern, Nathan C. Boles, Sally Temple
The paper compares single-cell transcriptomic and surface protein profiles of RPESC-RPE and PSC-RPE, finding differences in gene expression and surface markers that suggest functional and immunomodulatory differences.
bioRxiv · Mar 1, 2026 · PreprintCell Biology