SM Sajid Hasan

Structure-Guided Design and Dynamic Evaluation of VP4-Targeting siRNAs Against Rotavirus A

The paper designs and evaluates VP4-targeting siRNAs using computational methods to identify an optimized siRNA with improved structural compatibility and stability.

Linking Genomic Landscape to Disease Mechanism: Core Genetic Factors Underlying Pathogenesis and Antimicrobial Resistance in Diarrheal Pathogens

This study uses whole-genome sequencing and pan-genome analysis of Bangladeshi diarrheal pathogens to identify core genes involved in pathogenesis and antibiotic resistance.

APDeeM: A machine Learning strategy towards Effective Peptide Vaccine Candidates Identification against Different Types of Viruses

The paper introduces APDeeM, an ensemble machine learning system for identifying antiviral peptide candidates, achieving high accuracy and efficiency compared to existing methods.

Dissecting Breast Cancer Heterogeneity Through Transcriptomics Insights of Diverse Etiological Factors for Common Biomarker Discovery

The paper identifies shared genes across different breast cancer etiologies and suggests potential therapeutic targets through transcriptomic analysis and computational modeling.

Mapping the PTEN Mutation Landscape: Structural and Functional Drivers of Lung Cancer

The paper identifies fifteen PTEN mutations in lung cancer, seven of which significantly disrupt structure and function, supported by computational analysis and molecular simulations.