Centromere-proximal crossovers disrupt proper homologous chromosome disjunction during meiosis
Sucharita Sen, Sneha Sarkar, Gopika Menon, Mridula Nambiar
This study shows that increased centromere-proximal crossovers cause meiotic nondisjunction and biorientation in S. pombe, supporting the entanglement model and highlighting mechanisms of aneuploidy.
bioRxiv · Nov 18, 2024 · PreprintGenetics