Author

Sneha Shahu

Indian Institute of Science Bangalore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Mahipal GanjiiD· 2 shared Mansi Srivastava· 1 shared Prakshi Gaur· 1 shared Rohit Kumar SinghiD· 1 shared Saminathan RamakrishnaniD· 1 shared Sandeep ChoubeyiD· 1 shared Shreyasi Neogi· 1 shared Sreeja Baira· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Mahipal GanjiORCID

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2 papers

Recent·Most cited

A DNA-binding protein senses DNA superhelicity to switch between bridging and nucleoprotein filament formation

Sneha Shahu, Sreeja Baira, Sudhish Gupta, Mahipal Ganji

This study shows DNA superhelical polarity determines H-NS binding mode, affecting chromosomal domain organization and gene silencing.

bioRxiv · May 27, 2026 · PreprintBiophysics

Sequence-dependent co-condensation of Lsr2 with DNA elucidates the mechanism of genome compaction in Mycobacterium tuberculosis

Thejas Satheesh, Rohit Kumar Singh, Prakshi Gaur, Sneha Shahu, Saminathan Ramakrishnan, Mansi Srivastava, Shreyasi Neogi, Sandeep Choubey, Mahipal Ganji

This study investigates how Lsr2 protein interacts with DNA in Mycobacterium tuberculosis to compact the genome, revealing sequence-dependent co-condensation as a mechanism for gene regulation.

bioRxiv · Jan 6, 2025 · PreprintBiophysics