Mahipal Ganji

This study shows DNA superhelical polarity determines H-NS binding mode, affecting chromosomal domain organization and gene silencing.

This paper introduces speed-optimized DNA-PAINT sequences for high-plex super-resolution imaging and applies them to analyze nuclear organization changes under transcription inhibition.

The paper shows stress granules restrict dsRNA-led mitochondrial fragmentation by sequestering dsRNA, thereby suppressing inflammation and maintaining mitochondrial integrity.

This paper develops a polymer-based model to study how DNA sequence affects protein-DNA co-condensation, showing that sequence heterogeneity leads to multiple condensates.

This paper introduces Stack-pPAINT, a super-resolution imaging technique using DNA base-stacking interactions to detect proximal target molecules, demonstrating its application in visualizing microtubular structures.

This study shows that PfHP1 phase separation controls var gene silencing in P. falciparum by forming heterochromatin clusters, leading to antigenic variation.

This study investigates how Lsr2 protein interacts with DNA in Mycobacterium tuberculosis to compact the genome, revealing sequence-dependent co-condensation as a mechanism for gene regulation.

This study identifies Odoribacter splanchnicus as a broad-spectrum protective agent against Salmonella and Listeria infections by enhancing colonization resistance, preserving gut barrier integrity, and limiting pathogen proliferation and virulence.

This study investigates the structural and functional dynamics of Staphylococcus aureus α-hemolysin during membrane interaction, revealing its role in cell necrosis and pore formation.

This paper introduces SUM-PAINT, a high-throughput imaging method for single-protein spatial resolution, and discovers a new synapse type through extensive multiprotein analysis.

This study shows that condensin complexes use opposing ATPase sites to drive and dampen chromosome condensation, with condensin II playing a key role in decatenation and axis formation.