Diverse bacterial pattern recognition receptors sense the core phage proteome
Hyunbin Lee, Sofia Luengo-Woods, Jianxiu Zhang, Kira S. Makarova, Yuri I. Wolf, Collin Chiu, Simone A. Evans, Junyi Chen, Haopeng Xiao, Liang Feng, Eugene V. Koonin, Linyi Gao
The paper identifies 90 structurally distinct STAND NTPase families in bacteria and archaea that recognize phage proteins, revealing their role in antiviral defense.
Nature · Jul 29, 2026Peer-reviewedMolecular Biology