Cell BiologyCell & BiosciencePeer-reviewed
Inactivation of the Niemann Pick C1 cholesterol transporter 1 (NPC1) restricts SARS-CoV-2 infection
Piergiorgio La Rosa, Jessica Tiberi, Enrico Palermo…·Maria Teresa Fiorenza
This study shows that inactivating NPC1 reduces SARS-CoV-2 infection by trapping ACE2 in lysosomes and disrupting viral entry.
9 citations