Author

Mirko Cortese

University of Campania "Luigi Vanvitelli"ORCID 0000-0003-1786-4211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Anna Francesca Pacile· 1 shared Carmine SettembreiD· 1 shared Dimitrios MougiakakosiD· 1 shared Elena PolishchukiD· 1 shared Enrico PalermoiD· 1 shared Francesca NazioiD· 1 shared Francesca SaccoiD· 1 shared Giorgia MassacciiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Anna Francesca Pacile

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 11, 2026

LC3C-ATG4D regulatory axis supports coronavirus replication organelle formation independently of canonical autophagy

Štěpánka Vlachová, Lucia Iovine, Valentina Marano…·Mirko Cortese

This study identifies a non-canonical role for the LC3C-ATG4D axis in supporting coronavirus replication organelle formation, independent of canonical autophagy.

DOI 10.64898/2026.08.10.743971

humanexperimental assay

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Cancer BiologyLeukemiaPeer-reviewedJun 9, 2026

Organelle proteomics reveals novel metabolic vulnerabilities in FLT3-ITD cells

Valeria Bica, Anna Francesca Pacile, Martin Boettcher…·Francesca Sacco

The paper uses proteomics to identify metabolic vulnerabilities in FLT3-ITD AML cells, showing lipid restriction restores midostaurin sensitivity.

DOI 10.1038/s41375-026-03000-6

humanproteomics

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Cell BiologyCell & BiosciencePeer-reviewedDec 20, 2024

Inactivation of the Niemann Pick C1 cholesterol transporter 1 (NPC1) restricts SARS-CoV-2 infection

Piergiorgio La Rosa, Jessica Tiberi, Enrico Palermo…·Maria Teresa Fiorenza

This study shows that inactivating NPC1 reduces SARS-CoV-2 infection by trapping ACE2 in lysosomes and disrupting viral entry.

9 citations

humanbulk RNA-seq

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