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Sofie Wendel

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Evolutionary Biology· 1

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

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Agnieszka Sekowska· 1 shared Antoine Danchin· 1 shared Morten Helge Hauberg Norholm· 1 shared

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1 shared paperEvolutionary Biology

Agnieszka Sekowska

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Evolutionary BiologybioRxivFeb 26, 2016

Generation of mutation hotspots in ageing bacterial colonies

Agnieszka Sekowska, Sofie Wendel, Morten Helge Hauberg Norholm, Antoine Danchin

The paper isolates adaptive mutants from ageing bacterial colonies, identifies mutation hotspots, and shows mutations increasingly originate from 8-oxo-guanosine on the transcribed strand.

DOI 10.1038/s41598-016-0005-4

E. coliwhole-genome sequencing

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