Astrocytic MAOB-GABA axis as a molecular brake on repair following spinal cord injury
Hye Yeong Lee, Jung Moo Lee, Jiyeon Park, Heeyoung An, Eun Kyung Park, Sae Yeon Hwang, Sol lip Yoon, Gwang Yong Hwang, Keung Nyun Kim, Min‐Ho Nam, Seung Eun Lee, Hyunji Kang, Joungha Won, Bo Ko Jang, Elijah Hwejin Lee, , Yoon Soo Ha
This study identifies the astrocytic MAOB-GABA axis as a brake on spinal cord injury repair and shows that the inhibitor KDS2010 promotes recovery in animal models and has a safe profile in humans.
Signal Transduction and Targeted Therapy · Sep 10, 2025Peer-reviewedNeuroscience