Evaluation of NGS-based approaches for SARS-CoV-2 whole genome characterisation
Caroline Charre, Christophe Ginévra, Marina Sabatier, Hadrien Regue, Grégory Destras, Solenne Brun, Gwendolyne Burfin, Caroline Scholtès, Florence Morfin, Martine Valette, Bruno Lina, Antonin Bal, Laurence Josset
This study evaluates four NGS methods for SARS-CoV-2 whole-genome sequencing, finding that amplicon-based methods are most sensitive for low viral loads while mNGS and RVOP produce the most complete genomes for mid viral loads.
Virus Evolution · Jul 1, 2020Peer-reviewedGenomics