Preconditioning Matters: Enhancing or Impairing Antitumor Immunity with DC Vaccines
Eric Kwon, Shelby L. Namen, Colin J. Willoughby, Solomon Kang, Gaurav Pandey, Alexander Byungsuk Kim, Carl J. DeSelm
This study evaluates how different preconditioning strategies affect the efficacy of dendritic cell vaccines in a mouse tumor model, finding that low-dose radiation enhances antitumor immunity while cyclophosphamide reduces it.
bioRxiv · May 2, 2025 · PreprintImmunology