The pore-forming protein APOL7C ruptures Leishmania major-containing parasitophorous vacuoles in dendritic cells to promote IL-12 production and the induction of T helper type 1 immunity
Gerone A. Gonzales, Eymi Cedeño, Liam Wilkinson, Song Huang, Cassandra M. Wood, Neil T. McKenna, Robin M. Yates, Matheus Batista Heitor Carneiro, Nathan C. Peters, Johnathan Canton
bioRxiv · Dec 26, 2025 · PreprintCell Biology