Injectable adhesive hydrogel-drug complexes synchronize the release of chemoimmunotherapy to treat brain tumors in mice
Michelle Z. Dion, Alexander M. Cryer, Daniel Dahis, Pere Dosta, Andrea Li, Maria Poley, Núria Puigmal, Ivana Ling, Sonsoles Carrasco, Alexa Hinojosa, Yael Soria, Betty Tyler, Henry Brem, Natalie Artzi
This study develops injectable hydrogel-drug complexes that synchronize chemoimmunotherapy release to treat brain tumors in mice, achieving long-term survival and protection from rechallenge.
bioRxiv · Mar 31, 2025 · PreprintBioengineering