Author

Michelle Z. Dion

Brigham and Women's HospitalORCID 0000-0002-7189-561XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Natalie ArtziiD· 2 shared Alexa Hinojosa· 1 shared Alexander M. CryeriD· 1 shared Alexandru M. PleşaiD· 1 shared Andrea Li· 1 shared Andrew L. JiiD· 1 shared Anna MandinovaiD· 1 shared Asaf Ashkenazy-Titelman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Natalie ArtziORCID

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2 papers

Recent·Most cited

Human skin rejuvenation via mRNA

Li Li, Zhengkuan Tang, Xavier Portillo, Rohit Arora, Madeleine Yang, Esther Mintzer, Zhenrui Zhang, Stefano Sol, Fabiana Boncimino, Patrick Han, Michelle Z. Dion, Emery Di Cicco, D.D. Majewski, Asaf Ashkenazy-Titelman, Alexandru M. Pleşa, , George McDonald Church

This paper presents a single-cell atlas of skin aging and identifies ATF3 as a regulator of aging, leading to an mRNA-based treatment that reduces cell senescence and enhances skin rejuvenation.

Journal of Investigative Dermatology · Jul 21, 2026Peer-reviewedSynthetic Biology

Injectable adhesive hydrogel-drug complexes synchronize the release of chemoimmunotherapy to treat brain tumors in mice

Michelle Z. Dion, Alexander M. Cryer, Daniel Dahis, Pere Dosta, Andrea Li, Maria Poley, Núria Puigmal, Ivana Ling, Sonsoles Carrasco, Alexa Hinojosa, Yael Soria, Betty Tyler, Henry Brem, Natalie Artzi

This study develops injectable hydrogel-drug complexes that synchronize chemoimmunotherapy release to treat brain tumors in mice, achieving long-term survival and protection from rechallenge.

bioRxiv · Mar 31, 2025 · PreprintBioengineering