Cell BiologybioRxivPreprint
Large-scale endoplasmic reticulum membrane solidification spatially organizes proteins under thermal or metabolic stress
Paul M. Mueller, Melissa R. Mikolaj, Elmehdi Belbaraka…·Oliver Rocks
The paper identifies a temperature- and lipid saturation-dependent transformation of ER membranes into rigid tubes under stress, driven by lipid demixing and protein segregation.
DOI 10.64898/2026.04.09.717431