Cancer BiologybioRxivPreprint
Overcoming Resistance to Anabolic Selective Androgen Receptor Modulator (SARM) Therapy in Experimental Cancer Cachexia with Histone Deacetylase Inhibitor AR-42
Yu-Chou Tseng, Sophia G. Liva, Anees M. Dauki…·Christopher C. Coss
This study combines a SARM and HDAC inhibitor to improve anti-cachectic efficacy in a mouse model of cancer cachexia, showing significant improvements in bodyweight and muscle mass.
DOI 10.1101/214155