Author

Sophie Keightley

Salk Institute for Biological Studies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew M. LowyiD· 1 shared Casie S. KubotaiD· 1 shared Chelsea R. BottomleyiD· 1 shared Dannielle D. EngleiD· 1 shared Hervé TiriaciD· 1 shared Hyemin SongiD· 1 shared Jacob R. TremblayiD· 1 shared Jasper HsuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrew M. LowyORCID

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1 paper

Recent·Most cited

CA19-9 promotes liver metastasis of pancreatic cancer through E-selectin mediated extravasation

Satoshi Ogawa, Hyemin Song, Jasper Hsu, Vasiliki Pantazopoulou, Victoria Osorio-Vasquez, Casie S. Kubota, Jacob R. Tremblay, Chelsea R. Bottomley, Kathryn Lande, Jonathan Zhu, Kristina L. Peck, Yongjia Wang, Kassidy Curtis, Sophie Keightley, Ryan Tomita, , Dannielle D. Engle

This study shows CA19-9 promotes pancreatic cancer liver metastasis via E-selectin-mediated extravasation and AKT signaling, suggesting it as a therapeutic target.

bioRxiv · Apr 10, 2026 · PreprintCancer Biology