A molecular integrator of sleep duration and interruption
Elizabeth I. Tilden, Antonio J. Fontenele, Kane M. Goggans, Sophie Ma, Drake Gorecki, Zachary D. Berriman-Rozen, Anna Oldenborg, Woodrow L. Shew, Yao Chen
The paper identifies a molecular signal that encodes within-bout sleep history by showing PKA-SP decreases exponentially during sleep and integrates sleep duration and interruption.
bioRxiv · Jul 8, 2026 · PreprintNeuroscience