Peptidylglycine α-amidating monooxygenase restores brain microvascular blood flow and improves recovery following ischemic stroke
Ella Rose Matson, Yulia Ilina, Anania Tsinoglou, Emily Attrill, Sophie Mayne, Renee M. Ross, Michelle A. Keske, Brad A. Sutherland, Harald Juergen Hampel, Paul Kaufmann, Andreas Bergmann, Dino Premilovac
This study shows that administering PAM improves capillary blood flow and reduces infarct volume in rats after ischemic stroke, leading to better neurological recovery.
bioRxiv · Jun 18, 2026 · PreprintPhysiology