Author

Sophie McLaughlin

Cancer Research UK Scotland Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Catherine FickeniD· 1 shared Claire Kennedy DietrichiD· 1 shared Colin NixoniD· 1 shared Crispin J. MilleriD· 1 shared Daniel J. MurphyiD· 1 shared Douglas StrathdeeiD· 1 shared Emily HoeyiD· 1 shared Eva C. FreckmanniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Catherine FickenORCID

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1 paper

Recent·Most cited

Phenotype-dependent subtyping exposes high MYC activity as a targetable dependency in LuAd

Sarah Laing, Isabel Dye, Ryan M. Byrne, Eva C. Freckmann, Robin Shaw, Shahanawaz Ali, Sophie Heese, Yoana Doncheva, Catherine Ficken, Jennifer Doig, Sudhir B. Malla, Saira Ghafoor, Sophie McLaughlin, Colin Nixon, Graeme Clark, , Daniel J. Murphy

The paper identifies high MYC activity as a targetable feature in lung adenocarcinoma using phenotype-based subtyping and shows sensitivity to a dual inhibitor of MYC co-factors.

bioRxiv · May 1, 2026 · PreprintCancer Biology