Cardiac Magnetic Resonance Studies in a Large Animal Model that Simulates the Cardiac Abnormalities of Human Septic Shock
Verity J. Ford, Willard N. Applefeld, Jeffrey Wang, Junfeng Sun, Steven B. Solomon, Stanislav Sidenko, Jing Feng, Cynthia Sheffield, Harvey G. Klein, Zu‐Xi Yu, Parizad Torabi‐Parizi, Robert L. Danner, Vandana Sachdev, Michael A. Solomon, Marcus Y. Chen, Charles Natanson
This study uses cardiac magnetic resonance imaging in a canine sepsis model to show that ventricular wall edema and structural changes, not preload or afterload, explain differences in cardiac function and survival outcomes during sepsis.
bioRxiv · Feb 5, 2024Physiology