APP-CTFβ/C99 oligomers drive synaptic vesicle tethering through C-terminal interactions
Akshay Kapadia, Elena Cijffers, Stanley Van, Anne‐Sophie Hafner
The paper shows that APP-CTFβ oligomers enhance synaptic vesicle tethering and release through C-terminal interactions, contributing to neuronal hyperactivity.
bioRxiv · Jun 30, 2026 · PreprintNeuroscience