Anne‐Sophie Hafner

The paper shows that APP-CTFβ regulates glutamatergic synaptic transmission and that Aβ counteracts its hyperexcitability effects in Alzheimer's disease.

This paper presents a protocol for generating and using plasma membrane sheets to study membrane protein dynamics and synaptic vesicle recruitment in native membrane environments.

The paper shows that APP-CTFβ oligomers enhance synaptic vesicle tethering and release through C-terminal interactions, contributing to neuronal hyperactivity.

The paper introduces an extended SIM-Pull protocol to study synaptic protein complexes and vesicle recruitment using TIRF microscopy.

The paper develops a computational model to explain how local translation of CNIH-2 affects the trafficking and kinetics of different AMPAR subtypes during long-term potentiation.

The paper demonstrates that local protein synthesis occurs in both pre- and postsynaptic compartments of neurons, including excitatory and inhibitory axon terminals.

The paper proposes a mathematical model of synaptic competition for neurotransmitter receptors, showing how receptor dynamics influence synaptic plasticity and heterosynaptic plasticity.