Lipid metabolic stress in development defines which genetically-susceptible DYT-TOR1A mice develop disease
Ana Catarina Carapinha Cascalho, Joyce Foroozandeh, Stef Rous, Natalia Martínez Vizcaíno, Sandra F. Gallego, Rose E. Goodchild
The paper shows that genetic susceptibility to DYT-TOR1A dystonia in mice depends on developmental lipid metabolic stress, which is influenced by sex and maternal diet.
bioRxiv · Mar 18, 2020 · PreprintNeuroscience