Human placental stem cells induce a novel multiple myeloid cell-driven immunosuppressive program that ameliorates proinflammatory CNS pathology
Heela Sarlus, Yuxi Guo, Stefan Bencina, Keying Zhu, Vijay Joshua, Giulia Adriana Virgilio, Yufei Cheng, Jianing Lin, Jin-Hong Min, Irene Benito‐Cuesta, Valerie Suerth, Paula Trigo-Alonso, Olivia G. Thomas, Urszula Rykaczewska, André Ortlieb Guerreiro Cacais, , Robert Adam Harris
This study shows that human amniotic epithelial cells reduce CNS inflammation in MS by inducing immunosuppressive myeloid cells and resolving inflammation.
bioRxiv · Jun 14, 2025 · PreprintNeuroscience