Revealing the host antiviral protein ZAP-S as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting
Matthias M. Zimmer, Anuja Kibe, Ulfert Rand, Lukáš Pekárek, Liqing Ye, Stefan Buck, Redmond P. Smyth, Luka Čičin‐Šain, Neva Caliskan
The paper identifies ZAP-S as a host protein that inhibits SARS-CoV-2 programmed ribosomal frameshifting, reducing viral replication.
Nature Communications · Dec 10, 2021Peer-reviewedMolecular Biology