Neva Caliskan

This paper shows AcrVIB1 inhibits CRISPR-Cas13b by promoting unproductive crRNA binding and degradation, revealing a mechanism to suppress immune defense.

The paper expands the known range of nidovirus genomes up to 64 kb and identifies host constraints and new replicase expression modes in giant invertebrate nidoviruses.

This paper develops a reverse genetics platform for SARS-CoV-2 to generate recombinant viruses and study their replication and phenotypic effects.

The paper identifies ZAP-S as a host protein that inhibits SARS-CoV-2 programmed ribosomal frameshifting, reducing viral replication.

This paper elucidates the structural basis of how the Cardiovirus 2A protein regulates gene expression by interacting with RNA elements and ribosomes.

This study investigates how the 2A protein of Theilovirus stimulates ribosomal frameshifting by analyzing its interaction with an RNA pseudoknot and using ribosome profiling.