Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets
Shilu Zhang, Saptarshi Pyne, Stefan Pietrzak, Spencer Halberg, Sunnie Grace McCalla, Alireza Fotuhi Siahpirani, Rupa Sridharan, Sushmita Roy
This paper introduces scMTNI, a framework to infer cell type-specific gene regulatory networks on cell lineages using scRNA-seq and scATAC-seq data, showing its effectiveness on simulated and real datasets.
bioRxiv · Jul 25, 2022 · PreprintBioinformatics