Khoa A. Tran

This study expands the HIF-2α proteomic interactome using TurboID proximity labeling, identifying 329 novel interactors and linking some to poor patient survival in breast cancer.

This study determines the cryo-EM structure of NAT10 bound to a cytidine-CoA probe, revealing its mechanism for RNA N4-cytidine acetylation and its role in cellular processes.

This study identifies NUCKS1 as a novel SIRT7 interactor that promotes chromatin binding during senescence and liver aging, leading to metabolic and inflammatory gene expression.

This study identifies reprogramming checkpoints in iPSC generation by analyzing single-cell transcriptomes and reveals key gene interactions and regulatory mechanisms.