Fgf8 dosage regulates jaw shape and symmetry through pharyngeal-cardiac tissue relationships
Nathaniel Zbasnik, Katie Dolan, Stephanie A. Buczkowski, Rebecca M. Green, Benedikt Hallgrímsson, Ralph Marcucio, Anne Moon, Jennifer L. Fish
This study shows that reduced Fgf8 dosage causes asymmetric jaw development in mice, with left-side defects more severe than right-side, and links these asymmetries to heart development.
Developmental Dynamics · May 26, 2022Peer-reviewedDevelopmental Biology