The gastrin-releasing peptide regulates stress-enhanced fear and dopamine signaling
Yoshikazu Morishita, Ileana Fuentes, John S. Favate, Ko Zushida, Akinori Nishi, Charles Hevi, Noriko K. Goldsmith, Steven G. Buyske, Stephanie E. Sillivan, Courtney A. Miller, Eric R. Kandel, Shusaku Uchida, Premal Shah, Gleb P. Shumyatsky
This study shows that mice lacking the gastrin-releasing peptide gene exhibit enhanced fear conditioning and impaired extinction, with reduced dopamine-related gene transcription in the basolateral amygdala during stress-enhanced fear learning.
bioRxiv · Dec 31, 2020 · PreprintNeuroscience