Eric R. Kandel

The paper identifies circRNA hypomethylation in the human amygdala linked to FKBP5 in alcohol use disorder, with replication in an animal model.

This study investigates the role of SUMO2/3 modification in mitigating Tau-induced synaptic and cognitive dysfunction in disease models.

The paper identifies a direct lateral entorhinal cortex to hippocampal CA2 circuit that conveys social information necessary for social memory, distinct from novelty detection pathways.

This study investigates the effects of deep brain stimulation (DBS) on cocaine self-administration in cocaine-dependent rats and finds it increases cocaine intake but raises GluR1 levels in the central nucleus of the amygdala.

This study maps mitochondrial morphology in different neuronal compartments of the aging mouse hippocampus using 3D electron microscopy, revealing age-related differences in mitochondrial structure across cell types.

This paper identifies a novel vCA1[->]pPVN circuit that modulates both learned and innate fear by regulating neuronal activity in the PAG.

This study shows that mice lacking the gastrin-releasing peptide gene exhibit enhanced fear conditioning and impaired extinction, with reduced dopamine-related gene transcription in the basolateral amygdala during stress-enhanced fear learning.

The paper investigates the role of CPEB3's low complexity motif in its localization to P bodies and its function in local protein synthesis in neurons.

The paper shows that place-cell activity in mice is modulated by heading direction relative to a reference point.