Complement modulation synergizes with therapeutic hypothermia in a rat model of neonatal HIE
Angela Saadat, Haree K. Pallera, Frank A. Lattanzio, Dania Jacubovich, Stephanie Newman, Meghana Kunam, Andreea Ioana Necula, Aliyah Mohammed, Tushar A. Shah
This study shows that combining complement modulation with therapeutic hypothermia improves outcomes in a rat model of neonatal HIE, with sex-specific effects.
bioRxiv · Apr 10, 2026 · PreprintNeuroscience