Genetic & Genomic MedicinemedRxivPreprint
PD-L1-linked spatial decoupling of tumour-immune interactions in EBV-positive DLBCL
Axel Künstner, Matthias Kümmel, Anke Fähnrich…·Niklas Gebauer
The paper investigates how PD-L1 genomic gains in EBV-positive DLBCL alter spatial tumour-immune interactions, revealing immune evasion through fibroblast exclusion, metabolic suppression, and T-cell exhaustion.
DOI 10.64898/2026.07.02.26357123