Phosphoproteomics Reveals a Distinct Mode of Mec1/ATR Signaling in Response to DNA End Hyper-Resection
Ethan James Sanford, William J. Comstock, Vitor Marcel Faça, Stephanie Vega, Robert Gnügge, Lorraine S. Symington, Marcus Bustamante Smolka
This study identifies a distinct Mec1/ATR signaling mode triggered by DNA end hyper-resection, showing its role in regulating HR-mediated DNA repair through phosphorylation of the STR complex.
The EMBO Journal · Mar 25, 2021Peer-reviewedMolecular Biology