Preclinical characterization of AT-03, a novel Serum Amyloid P fusion protein that demonstrates pan-amyloid binding and removal
Christophe Sirac, Gilles Roussine Codo, Arnaud Jaccard, Sébastien Bender, Gemma Martinez-Rivas, Frank Bridoux, Marie Clavel, Camille Villesuzanne, Oussama Taoui, Claire Carrion, Gregory Bell, Spencer D. Guthrie, Suganya Selvarajah, Andrew Vick, Stephen J. Kennel, , Jonathan S. Wall
This paper characterizes AT-03, a novel fusion protein that binds and removes various amyloid types, showing therapeutic efficacy in a mouse model.
bioRxiv · Dec 25, 2025 · PreprintPathology