Hidden in plain sight: Bacterial genomes reveal thousands of lytic phages with therapeutic potential
Alexander Perfilyev, Anastasiya Gæde, Steve Hooton, Sara Ahmed Zahran, Caroline S Winther-Have, Panos G. Kalatzis, Rodrigo Ibarra Chavez, Rachael C. Wilkinson, Anisha M. Thanki, Bent Petersen, Zhengjie Liu, Qing Zhang, Qianghua Lv, Yuqing Liu, Adriano M. Gigante, , Thomas Sicheritz‐Pontén
The paper identifies thousands of lytic phage genomes within bacterial assemblies, expanding known phage diversity and suggesting clinical isolates may contain therapeutic phage candidates.
bioRxiv · May 6, 2025 · PreprintMicrobiology