SUMOylation of NaV1.2 channels regulates the velocity of backpropagating action potentials in cortical pyramidal neurons
Oron Kotler, Yana Khrapunsky, Arik Shvartsman, Hui Dai, Leigh Daniel Plant, Steven A.N. Goldstein, Ilya A. Fleidervish
The paper shows SUMOylation of NaV1.2 channels increases backpropagation speed of action potentials in cortical neurons by enhancing persistent sodium current.
eLife · Feb 16, 2023Peer-reviewedNeuroscience